Guangdong, China
Business Type:
Trading Company
Business Range:
Agriculture & Food, Chemicals, Health & Medicine, Manufacturing & Processing Machinery
Registered Capital:
147802.18 USD
Plant Area:
85 square meters
Management System Certification:
ISO 9001, ISO 9000, ISO 14001, ISO 14000, ISO 20000, OHSAS/ OHSMS 18001, HSE, ISO 14064, ...
Export Year:
2010-10-01
OEM/ODM Service
Sample Available

Bupropion Hydrochloride, Phenibut, Piracetam manufacturer / supplier in China, offering Antidepressant Drug Bupropion Hydrochloride CAS 31677-93-7 for Medical Use, USP Standard Dexmedetomidine HCl Dexmedetomidine Hydrochloride for Antihypertension CAS 145108-58-3, China Supply Bicalutamide Powder CAS 90357-06-5 for Anti-Prostate Cancer Drugs and so on.

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Antidepressant Drug Bupropion Hydrochloride CAS 31677-93-7 for Medical Use

Min. Order / Reference FOB Price
10 g US $1/ g
Port: Shenzhen, China
Production Capacity: 50kg/Month
Payment Terms: T/T, Western Union, Money Gram
Powder: Yes
Customized: Non-Customized
Certification: GMP, ISO 9001, USP, BP
State: Solid
Purity: >99%
Product Name: Bupropion Hydrochloride

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Basic Info.

Model NO.
31677-93-7
CAS
31677-93-7
Wickr
Aimeepharma
Trademark
Quanao
Transport Package
25kg/Drum
Specification
foil bag
Origin
China
Antidepressant Drug Bupropion hydrochloride CAS 31677-93-7 For Medical Use
 

Quick detail 

 

Bupropion Hydrochloride Basic Info

Product Name: Bupropion hydrochloride
Synonyms: (+-)-alpha-tert-butylamino-3-chloropropiophenonehydrochloride;2-(tert-butylamino)-3'-chloro-,hydrochloride,(+-)-propiophenon;m-chloro-alpha-tert-butylaminoprophenonehydrochloride
CAS:31677-93-7
MF:C13H19Cl2NO
MW:276.2
EINECS:250-759-9

Bupropion hydrochloride Chemical Properties

Chemical Properties White Crystalline Powder
Melting point 233-234 °C
Fp 9ºC
solubility ethanol: 193 mg/mL solutions may be stored for several days at 4 °C.
Water Solubility Soluble in water (>25 mg/ml), ethanol 193mg/ml, 0.1 N HCl 333 mg/ml

 

Bupropion Hydrochloride Specification

Product nameBupropion HydrochlorideBatch no20170404
Manufacture dateApr.05.2017Retest DatApr.04,20120Report dateApr.15,2017
Batch size126.27kgStandardUSP39
Test results
ItemsSpecificationsResults
AppearanceWhite powderWhite powder
SolubilitySoluble in water,ethanol and 0.1Nhydrochloric acidConforms
IdentificationIR absoption:Matches with standardConforms
HPLC RT:Matches with standardConforms
A solution of 1mg/ml in water meets the requirement of the silver nitrate precipitate test for chlorideConforms
Related compoundsTLCm-chlorobenzoic acid:NMT0.2%0.15%
Any other individual impurity:NMT0.1%None detected
HPLCImpurity-A:NMT0.2%0.05%
Impurity-B:NMT0.2%None detected
2-(tert-butylamino)propiophenone bydrochloride:NMT 0.5%None detected
1-(3-chlorophenyl)-1,2-propanedione:NMT0.2%None detected
2-(tert-butylamino)-2-chloropropionphenone hydrochloride:NMT0.1%None detected
3'-Chloropropiophenone:NMT0.1%None detected
2-bromo-3'-chloropropiophenone:NMT0.1%None detected
2-(tert-butylamino)-3',4'-chloropropiophenone hydrochloride:NMT0.2%None detected
2-(tert-butylamino)-3',5'-chloropropiophenone hydrochloride:NMT0.2%None detected
Any other individual impurity:NMT0.1%0.03%
Total unidentified impurities:NMT0.3%0.04%
Total impurities:NMT1.0%0.24%
Residual solvents(GC)Dichloromethane:NMT300ppm135ppm
Isopropanol:NMT3000ppm270ppm
Water(KF)NMT0.5%0.08%
Assay(HPLC)NLT98.0%and NMT102.0%(on anhydrous basis)99.5%
PackagingPreserve in well-closed,light-resistant containers
ConclusionThe product complies with the specification of USP31 standard.

Antidepressant Drug Bupropion Hydrochloride CAS 31677-93-7 for Medical Use
 

Bupropion hydrochloride Uses

An inhibitor of dopamine and SLC6A2. A selective inhibitor of dopamine uptake. An antidepressant of the aminoketone class; aid in smoking cessation

Biological Activity Non-selective inhibitor of dopamine and noradrenalin transporters (K i values are 1.4, 2.8 and 45 μ M for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine receptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo.

 

How to dose Bupropion HCl?

The usual adult dose is 300 mg/day, given 3 times daily. Dosing should begin at 200 mg/day, given as 100 mg twice daily. Based on clinical response, this dose may be increased to 300 mg/day, given as 100 mg 3 times daily, no sooner than 3 days after beginning therapy.

Increases in dose should not exceed 100 mg/day in a 3-day period. Gradual escalation in dosage is also important if agitation, motor restlessness, and insomnia, often seen during the initial days of treatment, are to be minimized. If necessary, these effects may be managed by temporary reduction of dose or the short-term administration of an intermediate to long-acting sedative hypnotic.
 


What are the side effects?

Less serious side effects may include:
dry mouth, nausea, stomach pain;
headache, dizziness, ringing in your ears;
loss of interest in sex;
sore throat, muscle pain;
mild itching or skin rash, increased sweating, increased urination; or changes in appetite, weight loss or gain.

 

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Our Advantages 


1. Quality Assurance


With our years of experience, advanced technology and continuous research, our quality can fully meet
the requirements of customers, many customers used our products and witness our good product's
quality. Whether it is powder or liquid, quality is the best.

2. Safe Transportation


Our mode of transport is taken according to each country's situation, while our package, according to
the latest customs situation, constantly updated, improved our packaging, safe delivery can be
guaranteed.

3. Customized Service


We have raw material, machine, lab, professional chemist and counselor ( Professor From Famous
University ), if you can offer us the Cook Recipes, even an idea, we can conduct the research as your
request. Research cost is in our charge.

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