Bodybuilding Growth Peptides 1mg/Vial Raw Peptides Gh Follistatin 344/Follistatin 315
|FOB Price:||US $1 / Piece|
|Min. Order:||10 Pieces|
|Min. Order||FOB Price|
|10 Pieces||US $1/ Piece|
|Port:||Hong Kong, Hong Kong|
|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: follistatin 344/Follistatin 315
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Appearance: Sterile Filtered White Lyophilized
- Payment: T/T, Western Union, Money Gram and Bitcoin
- Lead Time: Within 12 Hours Upon Receipt of Payment
- Trademark: yc
- Specification: 10g/bag
- HS Code: 2922199090
- Powder: Yes
- Certification: ISO 9001
- State: Solid
- Product: Follistatin 344
- Mini Order: 10g
- Delivery: EMS, DHL, TNT, FedEx, UPS
- Shipping Time: About 5 Working Days
- Transport Package: Foil Bag
- Origin: China
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 95.0%
Formulation: Lyophilized from a concentrated (1mg/ml) solution containing no additives. Solubility: It is recommended to reconstitute the lyophilized Follistatin in sterile 18M -cm H2O not less than 100 G/ml, which can then be further diluted to other aqueous solutions. Stability: Lyophilized Follistatin although stable at room temperature for 3 weeks, should be stored desiccated below -18ºC. Upon reconstitution FST should be stored at 4ºC between 2-7 days and for future use below -18ºC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
|Appearance||White to off white powder||Consistent|
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .
An earlier name for the same protein was FSH-suppressing protein (FSP). At the time of its initial isolation from follicular fluid, it was found to inhibit the anterior pituitary's secretion of follicle-stimulating hormone (FSH).
Follistatin works by binding to and inhibiting transforming TGF-β peptides such as myostatin which is responsible for regulating and limiting muscle growth. It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function. However, FSH levels that are too low can also negatively impact health and reproductive capabilities.
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