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Guangzhou Quanao Chemical Co., Ltd.

Follistatin 344, Fst 344, Human Growth Polypeptide manufacturer / supplier in China, offering 99% Human Growth Polypeptide Powder Follistatin 344 (1mg/vial) for Bodybuilding, Calcium Pyruvate Weight Loss Steroids Enhance Exercise Endurance 52009-14-0, CAS 5949-44-0 Testosterone Steroid Hormones Testosterone Undecanoate for Muscle Bodybuilding and so on.

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Supplier Homepage Product Human Growth Peptides 99% Human Growth Polypeptide Powder Follistatin 344 (1mg/vial) for Bodybuilding

99% Human Growth Polypeptide Powder Follistatin 344 (1mg/vial) for Bodybuilding

FOB Price: US $28 / vial
Min. Order: 1 gram
Min. Order FOB Price
1 gram US $28/ vial
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Production Capacity: 200kg/Month
Transport Package: Vial
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Follistatin 344
  • Synonyms: Fst, Fs, Activin-Binding Protein
  • Appearance: White Powder
  • Trademark: Quanao
  • HS Code: 3001200010
  • Product Name: Follistatin 344
  • Assay: 99%
  • Specification: 1mg/Vial, ISO, GMP
  • Origin: China
Product Description
99% Human Growth Polypeptide Powder Follistatin 344 (1mg/vial) for Bodybuilding


Product Details
Basic Info.
 
   Model NO.:Follistatin 344
   Producut Name:Follistatin 344
   Appearance:White Crystalline Powder
   Purity:99%
   Place of Origin:China
   Specifications:3000iu/Vials, 10vials/Box ; 1mg/vial
   Export Markets:Global
 
Additional Info.
 
   Trademark: Quanao
   Packing:Foil Bag or Tin
   Standard:10iu/vial, 10vial/box
   Origin:China
   HS Code:3001200010
   Production Capacity:10kg/Month


Product Description

99% Human Growth Polypeptide Powder Follistatin 344 (1mg/vial) for Bodybuilding
 
Name: Follistatin 344
Synonyms: FST, FS, Activin-binding protein.
Appearance: Sterile Filtered White Lyophilized (Freeze-Dried)
Manufacturer: Quanao
Purity (by HPLC): 99.00%
Source: Escherichia Coli
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation: Lyophilized from a concentrated (1mg / ml) solution containing no additives.
Solubility: It is recommended to reconstitute the lyophilized Follistatin in sterile 18MΩ-cm H2O not less than 100μg / ml, which can then be further diluted to other aqueous solutions.
Stability: Lyophilized Follistatin although stable at room temperature for 3 weeks.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC (b) Analysis by SDS-PAGE..
Storage Conditions: Aviod Shunshine and Keeping Stoppered
Packing: 1mg / vial, 2mg / vial
 
>Product Description:

Follistatin 344 
 
Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. 

Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the
non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. 

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.
 
Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).
 
 
>Application:
 
Follistatin 344 

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .
 
>Follistatin and Muscle Growth
 
Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth.  It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. 
In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.
 
 
Follistatin 344 Specifications:
 

Appearance
White to off white powderConsistent
Purity(HPLC)≥98%99%
Water<6.0%5.43%
Acetic Acid3.0-8.0%6.45%
Trifluoroacetic Acid<0.25%0.08%
Peptide≥80%88.45%
MSConsistentConsistent

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