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Guangzhou Quanao Chemical Co., Ltd.

Prilocaine, Local Anesthetic Drugs Prilocaine, 721-50-6 manufacturer / supplier in China, offering Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine, 99% Steroids Powder Testosterones Base for Bodybuilding CAS 58-22-0 Test Base, Hot Sales Steroids Nandrolone Phenylpropionate and so on.

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Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine

FOB Price: Get Latest Price
Min. Order: 10 gram
Port: Hong Kong, Hong Kong
Production Capacity: 1000kg/Month
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 721-50-6
  • Customized: Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • CAS: 721-50-6
  • Minimum Order Quantity: Negotiation Price:Negotiation
  • Delivery Time: Within 8 Hous After Receiving Your Payment
  • Shipment Method: UPS DHL FedEx TNT EMS Hkems Hongkong Post Eub Etk
  • Appearance: White Crystalline Powder
  • Transport Package: Discreet Ways of Packing for Customs Pass Guarante
  • Origin: Guangzhou
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP, SGS Ukas
  • State: Solid
  • Product Name: Prilocaine
  • Assay: 99%
  • Packaging Details: Discreet Ways of Packing for Customs Pass Guarante
  • Payment Terms: T/T, Western Union, Moneygram, Bitcoin
  • Test: Free Sample
  • Trademark: Quanao
  • Specification: 1kg foil bag
  • HS Code: 2942000000
Product Description
Top Grade  CAS 721-50-6 Local Anesthetic Drugs Low toxicity Prilocaine 

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Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine

Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine
Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine

Customer Feedback:

Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine

Disguised Product Show:

Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine


Items TestedSpecificationResult
CharactersWhite or almost white crystalline powderConfirms
Melting Point166ºC-169ºC166.5ºC-168.5ºC
SolubilityFreely soluble in water and in alcoholConfirms
Assay (HPLC)99.0--101.0% (calculated on the dried basis)99.6%
Loss on DryingNot more than 0.3%0.16%
Related substancesNot more than 1.0%0.11%
AcetoneNot more than 5000ppmconforms
EthanolNot more than 5000ppmconforms
Sulphated ashNot more than 0.15%conforms
Heavy MetalNot more than 0.001%<0.001%
ConclusionConforms USP36

What is Prilocaine ?

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Quick Details


Product Name



2-(propylamino)-o-propionotoluidid, xylonest

Assay (%)

≥ 99.00




White crystalline powder

Melting Point


Molecular Formula


Molecular Weight


Cas No.






Main Functions

Local anesthetic.


Pharmaceutical fields


Aluminum foil bag inside+ Carton box outside;1kg/bag,25kg/drum;

Shelf Life

36 months


Store in sealed containers at cool & dry place. Keep away from light, moisture, pest infestation.


prilocaine topical cream is used on the skin or in the genital area to cause numbness or loss of feeling before certain medical procedures. It is used to prevent pain caused by an injection, the drawing of blood from a vein, or minor surgeries such as removing warts. This medicine contains a mixture of two topical local anesthetics. It deadens the nerve endings in the skin.

Relieving pain of normal intact skin and numbing skin to pain from injections and other medical procedures.

prilocaine cream is a local anesthetic. It works by blocking nerves from transmitting painful impulses to the brain

Prilocaine ydrochloride Injection, USP, 4% is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection. See INDICATIONS AND USAGE for specific uses.


Prilocaine is a local anesthetic for the anesthesia's skin and tissues and cycles; this drug is usually provided as a topical application and comma cream; but it may also be available in injectable form and comma; should be specially trained The effect of the professional and the time management; its effect is not immediate and comma; but once a person experiences the relevant numbness, it may last for hours; during this time and the comma is important to pay attention to her health care provider's Advice so that she can avoid harming yourself and during the period;

Health care providers use propranolol to imply that they manage the place of injection or carry out certain procedures and periods of feeling; this drug is considered to be a local anesthetic because it is usually applied to the area of need and cycle; for example & comma if the dentist Use it and the comma he may inject the drug into his work area and the gingival near the periodic location;

In addition to injectable forms and commas, this drug can also be used as a cream and a period of time; cream is suitable for a particular area and period; injections and commas may take longer to take effect; its effects may be more limited and cycle; In the case of commas, once numbness begins, it may last for hours;

More Details

In some patients, metabolites of prilocaine may cause abnormal side effects of methemoglobinemia and may be treated with methylene blue.

Local anesthesia is a substance that causes sensory loss only in its application area without affecting consciousness. Most local anesthetic structures have an amino ester or aminoamide group attached to a hydrophilic (secondary or tertiary amine) and the other side of the hydrophobic group (aromatic compound).

Local anesthetics, long duration, low toxicity, chemical substances are also smaller for epidural anesthesia, block anesthesia and infiltration anesthesia.

Lidocaine and Prilocaine - Clinical Pharmacology

Mechanism of Action:

Lidocaine and Prilocaine cream, applied to intact skin under occlusive dressing, provides dermal analgesia by the release of Lidocaine and Prilocaine from the cream into the epidermal and dermal layers of the skin and by the accumulation of Lidocaine and Prilocaine in the vicinity of dermal pain receptors and nerve endings. Lidocaine and Prilocaine are amide-type local anesthetic agents. Both Lidocaine and Prilocaine stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.

The onset, depth and duration of dermal analgesia on intact skin provided by Lidocaine and Prilocaine cream, depends primarily on the duration of application. To provide sufficient analgesia for clinical procedures such as intravenous catheter placement and venipuncture, Lidocaine and Prilocaine cream, should be applied under an occlusive dressing for at least 1 hour. To provide dermal analgesia for clinical procedures such as split skin graft harvesting, Lidocaine and Prilocaine cream, should be applied under occlusive dressing for at least 2 hours. Satisfactory dermal analgesia is achieved 1 hour after application, reaches maximum at 2 to 3 hours, and persists for 1 to 2 hours after removal. Absorption from the genital mucosa is more rapid and onset time is shorter (5 to 10 minutes) than after application to intact skin. After a 5 to 10 minute application of Lidocaine and Prilocaine cream, to female genital mucosa, the average duration of effective analgesia to an argon laser stimulus (which produced a sharp, pricking pain) was 15 to 20 minutes (individual variations in the range of 5 to 45 minutes).

Dermal application of Lidocaine and Prilocaine cream, may cause a transient, local blanching followed by a transient, local redness or erythema.


Lidocaine and Prilocaine cream, is a eutectic mixture of lidocaine and prilocaine formulated as an oil in water emulsion. In this eutectic mixture, both anesthetics are liquid at room temperature (see DESCRIPTION) and the penetration and subsequent systemic absorption of both prilocaine and lidocaine are enhanced over that which would be seen if each component in crystalline form was applied separately as a topical cream.

Absorption- The amount of Lidocaine and Prilocaine systemically absorbed from Lidocaine and Prilocaine cream, is directly related to both the duration of application and to the area over which it is applied. In two pharmacokinetic studies, 60 g of Lidocaine and Prilocaine cream, (1.5 g lidocaine and 1.5 g prilocaine) was applied to 400 cm2 of intact skin on the lateral thigh and then covered by an occlusive dressing. The subjects were then randomized such that one-half of the subjects had the occlusive dressing and residual cream removed after 3 hours, while the remainder left the dressing in place for 24 hours. The results from these studies are summarized below.

Usage and Dosage

Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.

How to Use Lidocaine/ Prilocaine Cream

Use lidocaine/prilocaine cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with lidocaine/prilocaine cream. Talk to your pharmacist if you have questions about this information.

Wash and completely dry the area to be treated. Apply a thick layer of cream to the affected skin. Do not rub lidocaine/prilocaine cream into the skin.

Lidocaine/prilocaine cream should only be used on normal, unbroken skin. Do not apply to damaged skin.

Avoid getting lidocaine/prilocaine cream in your eyes, nose, or mouth. If you get lidocaine/prilocaine cream in your eyes, rinse them with plenty of water.

Wash your hands immediately after using lidocaine/prilocaine cream.

Discard unused medicine and packaging in the trash, out of the reach of children and away from pets.

If you miss a dose of lidocaine/prilocaine cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use lidocaine/prilocaine cream.

Order Guide

Q1: Have your Product Quality been Approved by Third Party Lab ?
A: Yes, All products are strictly tested by our QC , confirmed by QA and approved by third party lab in China , USA , Canada , Germany , UK , Italy , France etc. So you could be relieved to choose us.

Q2: Do you Accept Sample Order ?
A: Yes, we accept small order from 10g , 100g and 1kg for your evaluation quality of our goods.

Q3 :Can I get a sample ?
A: Of course. for most products we can provide you a free sample , while the shipping cost should undertake by you.

Q4:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card , we'd like to accept Western Union , Moneygram , T/T&Bitcoin.

Our Advantage

1. USA based delivery to ship , we could guarantee the 100% safe domestic shipping

2. We have storehouse in France , it was very convient for us to ship to EU ,the customs clearance is 99.99%

3. Special channel (Only from Quanao) ,please send message to us to know more about our process of orders .

Our Service

1.Quality Product and Good Price
We offer absolute high quality product in customized or non-customized.If there are any problems in quality,please contact me as soon as possible.

2.Fast&Secure Shipping
Generally,for small quantity product,the product will be shipped by courier.
For bulk goods,usually you will receive the product within 15 working days.
The rate of passing customs is more than 90%.

3.Reshipping Policy
Even for the worst situation when the product is blocked by the customs,we can reship the product without any extra payment for the product.

4.Technical Supports
Our lab can customize the right product and support u with our top specialists.So if u have a recipe and need help just inform us.We can make experiments and get a good result.

PS: Guangzhou Quanao Chemical Co.,Ltd,We have had experiences over 10 years for exporting Anabolic Steroids , peptides and Pharmaceutical intermediates in the whole world . Large qty need to be shipped to USA every month , our distributors have demands over $10000 for raws every month . No matter how big your order , we will have way to ship to you and guarantee the 100% safe for you .
EU market is also very hot selling . For example , UK,Latvia, Lithuania, Russia .The distributors came from these countries ,they bought raws can range $5000 to $20000, the finished products from them are very popular .

Top Grade CAS 721-50-6 Local Anesthetic Drugs Low Toxicity Prilocaine


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