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Guangzhou Quanao Chemical Co., Ltd.

Acadesine, CAS: 1379686-30-2, Reducing Fat Mass Chemicals manufacturer / supplier in China, offering Cardiovascular Diseases Treatment Acadesine Acadesine CAS: 2627-69-2, Male Gain Muscle Burning Fat White Powder Oxandrolone Anavar 53-39-4, High Quality Raw Materials L-Epinephrine Hydrochloride/ L (-) -Epinephrine 55-31-2 and so on.

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Supplier Homepage Product Pharmaceutical Intermediates Cardiovascular Diseases Treatment Acadesine Acadesine CAS: 2627-69-2

Cardiovascular Diseases Treatment Acadesine Acadesine CAS: 2627-69-2

FOB Price: US $1 / G
Min. Order: 10 G
Min. Order FOB Price
10 G US $1/ G
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Production Capacity: 3000kg/Month
Transport Package: as Your Request
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 2627-69-2
  • Brand: Yc
  • Apprarance: White Powder
  • Molecular Weight: 258.23
  • Specification: ISO9001, KOSHER, SGS
  • Name: Acadesine
  • CAS: 1379686-30-2
  • Molecular Formula: C9h14n4o5
  • Trademark: YC
  • Origin: China
Product Description
Acadesine
CAS: 2627-69-2 
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE 
EINECS: 220-097-5 
Molecular Formula: C9H14N4O5 
Molecular Weight: 258.23 
Storage Temp.: 20°c
Solubility H2O: >10 Mg/Ml
Melting Point: 214-215 ° C
Boiling Point: 726.3 ° C at 760 mmHg
Assay: 98% 
Apperance: White or off-white powder. 
Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase;ARASINE;Cardiovascular APIs;PI3K/Akt/mTOR
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases
Functions:AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
 
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